Nano Infusion: The Gentle First Step Toward Collagen Renewal

Nano Infusion: The Gentle First Step Toward Collagen Renewal

Posted by Jess Lauren on

At Periidot, I take a progressive, intentional approach to advanced skin treatments. Rather than jumping straight into the most intensive options, I believe in training and strengthening your skin step by step. That’s why Nano Infusion is often the first step in a long-term treatment plan that can lead to Microchanneling (collagen induction therapy).

Nano Infusion is gentle, non-invasive, and deeply effective. This treatment:

  • Enhances the delivery of active ingredients into the skin

  • Boosts hydration and smooths surface texture

  • Stimulates healthy skin function without downtime

By starting here, your complexion becomes more resilient, hydrated, and balanced—beautifully prepared for the deeper collagen-stimulating benefits of Microchanneling.

Nano Infusion vs. Microchanneling: What’s the Difference?

Both Nano Infusion and Microchanneling involve creating micro-channels in the skin, but they work at very different levels and serve different purposes in a treatment journey.

Microchanneling (Collagen Induction Therapy):

  • A form of microneedling that uses a controlled stamping method for consistency and precision

  • Semi-invasive, with needles ranging from 0.25–2.5mm in depth

  • Penetrates into the dermis to trigger collagen and elastin production through controlled microinjury

  • Typically requires numbing cream for comfort

  • May involve temporary redness or downtime

  • Excellent for improving fine lines, wrinkles, acne scars, uneven texture, and overall firmness

DermaChannel Nano Infusion:

  • Non-invasive, using a mono-crystalline silicon tip

  • Less than 0.25mm in depth—exfoliates without puncturing into the dermis

  • No numbing cream required

  • No downtime

  • Ideal for enhancing penetration of targeted serums and boosting hydration

How Nano Infusion Works

Nano Infusion uses a precision mono-crystalline silicon array to create microscopic channels in the very top layer of the skin (the epidermis). These channels:

  • Gently exfoliate dead surface cells

  • Allow active ingredients to absorb with greater precision and effectiveness

  • Stimulate natural skin function without causing injury or inflammation

This process—sometimes called microporation—is not the same as puncturing the skin. Instead, it primes the surface so your skin drinks in nourishing ingredients and strengthens its barrier.

Because it allows serums and active products to penetrate more deeply, Nano Infusion can also assist with softening fine lines and wrinkles, evening skin tone, and enhancing overall radiance.

Preparing for Advanced Treatments

Nano Infusion is often the first step in a progressive treatment plan. By strengthening barrier function and improving hydration, it helps ensure your skin is ready for more advanced therapies such as:

  • Microchanneling (Collagen Induction Therapy): This semi-invasive treatment works deeper in the dermis, creating controlled microinjuries that stimulate new collagen and elastin production. Over time, Microchanneling can improve fine lines, wrinkles, acne scarring, enlarged pores, loss of elasticity, and uneven tone.

  • Stronger Peels: Chemical exfoliation at a deeper level to target pigmentation, congestion, or signs of aging.

  • Hydrodermabrasion: A combination of physical and chemical exfoliation paired with simultaneous serum infusion. This resurfacing treatment deeply cleanses, polishes, and nourishes the skin for a radiant, refreshed result.

By starting with Nano Infusion, I can assess how your skin responds and set the stage for these more intensive treatments—ensuring safer, more radiant long-term results.

Why Start With Nano Infusion?

Think of Nano Infusion as “training” your skin. It’s an excellent stand-alone treatment for hydration, radiance, and texture—but it also plays a key role in preparing the skin for more intensive treatments.

  • Progressive Treatment Planning: Nano Infusion is a smart way to assess how your skin responds before moving on to microchanneling, chemical peels, or hydrodermabrasion.

  • Barrier Support: By enhancing hydration and balancing skin function, Nano Infusion ensures your skin is strong enough to handle more collagen-stimulating therapies.

  • Targeted Benefits: Beyond hydration, Nano Infusion can visibly soften fine lines and wrinkles by helping your skin absorb active serums more effectively.

  • No Downtime: Perfect if you want visible results without recovery time, making it an accessible treatment for busy schedules.

Nano Infusion is often a great first step to more advanced treatments. However, to maximize results and protect your skin long term, I always emphasize the essentials: consistent barrier-supportive homecare and daily SPF are non-negotiable foundations for any advanced treatment plan.

Pairing Nano Infusion with Targeted Serums

One of the biggest advantages of Nano Infusion is its ability to boost the absorption and efficacy of active ingredients. Because you’re opening micro-channels in the uppermost layer of skin, serums can penetrate more deeply and act more effectively. Below are a few of my go-to Le Mieux formulations (which I use in treatments and offer at Periidot.com) that pair beautifully with Nano Infusion. Each of these serums are based in a Hya10 complex created with ten different forms and molecular weights of hyaluronic acid:

  • Le Mieux TGF‑B Booster — A silky, youth-enhancing serum powered by transforming growth factor-beta. Helps plump fine lines, firm skin, and enhance the results of whatever goes on top.

  • Le Mieux EGF‑DNA Serum — Infused with epidermal growth factor and DNA-supportive ingredients; great for resilience, regeneration, and skin strength.

  • Le Mieux StemCell EGF Ampoules — A potent anti-aging formula combining stem cells and EGF to support collagen production, tone, and renewal.

Why These Serums Work Well with Nano Infusion

  1. Enhanced delivery
    Nano Infusion primes the skin so these actives (growth factors, hyaluronic acid, stem cells) can travel deeper—maximizing their effect.

  2. Complementary actions

    • Growth factor / EGF formulas help with regeneration, wound-healing signaling, and repair.

    • Hyaluronic acid helps lock in moisture and plump from within, giving that “bounce.”

    • Stem cell ingredients add support for cellular renewal and defense.

  3. Synergy over time
    When paired consistently, this strategy means your skin is not only receiving nutrients more efficiently, but also responding and repairing more effectively. Over repeated treatments, those small gains compound.

  4. Controlled environment
    Because Nano Infusion doesn’t go deep enough to disrupt the dermis, using these serums in a well-controlled session reduces the risk of irritation or over-processing.

The Takeaway

I see Nano Infusion as both a highly effective treatment on its own and an essential first step in a thoughtful, progressive skin journey. By strengthening your skin barrier, enhancing hydration, and preparing your complexion for deeper rejuvenation, it ensures that when you’re ready for Microchanneling, your results are more radiant and long-lasting.

Ready to experience Nano Infusion for yourself? Book your treatment today

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